Summary

A person is concerned about a relative with depression who has become suspicious of doctors and stopped medication and appointments. Earlier improvement has disappeared, and the family wants to know how to help.
The answer explains that depression can have different presentations and may sometimes include psychotic symptoms or overlap with other conditions.
It recommends returning to the doctor for reassessment of the new paranoia, with gentle family support and possible involvement of a therapist, rather than assuming the earlier treatment remains sufficient.
Question
Reader · Identity withheldA close family member has been diagnosed with depression. He was prescribed medication, which did help him when he took it.
Recently, he has been showing signs of paranoia, thinking that the doctors are drugging him and that there is a conspiracy against him. This paranoia is influencing him not to take his medication or see a doctor.
The improvement that was made previously has disappeared. As a loved one, I do not know what to do. What is the best way to approach this situation and help him before it is too late?
Answer
Mark Vigil Dombeck, Ph.D.Depression comes in many different forms. Some depressions are characterized by sad mood, while others involve osscilations between sad and euphoric moods.
Other depressions involve angry feelings. Very severe depressions can sometimes include psychotic features such as hallucinations and delusions (including paranoid delusions).
Depressive symptoms can also combine with symptoms from other disorders (such as schizophrenia) to produce mixed disorders (such as Schizoaffective Disorder which combines symptoms from schizophrenia and depression).
Different forms and presentations of depression are best addressed using different treatments (different combinations of medication and/or psychotherapy) for optimal results.
The proper course of action is to get your relative back to see the doctor so that the doctor knows about the paranoia symptoms in addition to the depressed mood symptoms.
A medication change may be in order. Your relative may view such a re-assessment as part of a plot to harm him, but this sort of thinking needs to be *gently* challenged so that you all stay with reality as best as possible and not give in to what is patently wrong.
Thereafter, it will be helpful to monitor that your relative is actually taking his medication as prescribed (if possible). In the best case, both family members and an outside objective therapist can be helping out; the therapist sees the patient once a week and can pick up on things that family members might be too close to see.
Subject matter expert
Simone Hoermann Ph.D.
Personality disorders, anxiety, and depression
View experience

