{"formatVersion":"1.1","id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects","path":"/library/verapamil-uses-dosage-side-effects","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects","title":"Verapamil","family":"Library detail","description":"Verapamil is a calcium channel blocker drug used to treat heart conditions such as angina. Learn more about how it is used, interactions, and more.","language":"en-US","access":{"audience":"custom-shared-preview","indexable":true},"provenance":{"sourceUrl":"https://www.mentalhealth.com/library/verapamil-uses-dosage-side-effects","wordpressId":"8574","contentCompleteness":"complete","dateScope":"original-source"},"authors":[{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/naomi-carr#person","name":"Naomi Carr","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/naomi-carr"}],"reviewer":{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid#person","name":"Leila Khurshid, Pharm.D.","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid"},"dates":{"datePublished":"2024-08-06T23:36:40Z","dateModified":"2025-08-13T12:17:13Z"},"content":{"html":"<nav aria-label=\"Breadcrumb\" class=\"breadcrumbs\"><ol><li><a href=\"/\">Home</a></li><li><a href=\"/library\">Library</a></li><li><a href=\"/library/medications\">Medications</a></li><li><span aria-current=\"page\">Verapamil</span></li></ol></nav><div class=\"article-page article-standard\" data-library-standard=\"\"><div class=\"article-main-grid\"><header class=\"article-heading\"><h1>Verapamil</h1><p class=\"article-inline-credits\"><span>Written by <a class=\"article-credit-person\" href=\"/people/naomi-carr\"><img alt=\"\" height=\"22\" loading=\"lazy\" src=\"/assets/optimized/47686b37ff1465ff6711c0b5.jpg\" width=\"22\" decoding=\"async\">Naomi Carr</a></span><span>Medically reviewed by <a class=\"article-credit-person\" href=\"/people/leila-khurshid\"><img alt=\"\" height=\"22\" loading=\"lazy\" src=\"/assets/optimized/90339bb61ace127cee8df5f2.webp\" width=\"22\" decoding=\"async\">Leila Khurshid, Pharm.D.</a></span></p><div class=\"article-dates\"><span>Published on <time datetime=\"2024-08-06T23:36:40Z\">August 6, 2024</time></span><span aria-hidden=\"true\"> · </span><span>Updated on <time datetime=\"2025-08-13T12:17:13Z\">August 13, 2025</time></span></div></header><div class=\"article-jumpbar\"></div><div class=\"article-layout\"><div class=\"article-reading\"><article class=\"prose\" id=\"article-content\"><div class=\"article-intro\" data-source-field=\"hero\"><p>Verapamil is a calcium-channel blocker used for treating various heart conditions and sometimes for the treatment of bipolar disorder. Take this medication exactly as prescribed. Always consult your doctor or pharmacist before starting a new medication (prescribed or over the counter) while taking verapamil, as adverse effects can occur.</p></div><figure class=\"article-feature\"><img alt=\"A healthcare professional rests a reassuring hand on a patient's knee during a consultation.\" decoding=\"async\" height=\"798\" loading=\"eager\" src=\"/assets/optimized/4d99fc919c337ed6d0164eab.webp\" width=\"1200\"></figure><section aria-labelledby=\"key-takeaways\" class=\"article-takeaways\"><h2 id=\"key-takeaways\">Key takeaways</h2><ul><li>Verapamil is a calcium-channel blocker used for heart conditions and sometimes prescribed off-label for bipolar disorder.</li><li>Formulations and treatment plans vary, and medication interactions can change its effects or increase risks.</li><li>Medical supervision is important because adverse cardiovascular effects and overdose can be serious.</li></ul></section><h2 id=\"verapamil-brand-names\">Verapamil brand names</h2><ul class=\"wp-block-list\">\n<li>Calan</li>\n<li>Calan SR</li>\n<li>Covera HS</li>\n<li>Isoptin (discontinued)</li>\n<li>Verelan</li>\n<li>Verelan PM</li>\n</ul><h2 id=\"what-is-verapamil-prescribed-for\">What is verapamil prescribed for?</h2><p>Verapamil is prescribed to treat various heart conditions, including angina, high blood pressure, and tachycardia.<sup><a class=\"article-inline-link article-citation\" href=\"#verapamil\" data-reference-link=\"\" aria-label=\"Source: Fahie, S., &amp; Cassagnol, M. (2022). Verapamil. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from National Library of Medicine\">[1]</a></sup></p><p>Verapamil has been investigated for bipolar disorder, but it is not an established treatment for acute mania. [2][3]</p><p>Verapamil is not FDA-approved for bipolar disorder. A systematic review found no evidence of benefit in six controlled trials for acute mania. Its psychiatric use remains off-label, with limited evidence; any proposed use needs an individualized discussion with the prescriber. <a class=\"article-inline-link article-citation\" href=\"#systematic-review-calcium-channel-antagonists-bipolar-disorder-some-considerations\" data-reference-link=\"\" aria-label=\"Source: Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. Molecular Psychiatry, 21(10), 1324–1332. Retrieved from A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…\">[2]</a><a class=\"article-inline-link article-citation\" href=\"#verapamil-treatment-women-bipolar-disorder\" data-reference-link=\"\" aria-label=\"Source: Cipriani, A., Saunders, P. T. K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development. Molecular Psychiatry, 21(10), 1324–1332. Accessed October 8, 2026.\">[3]</a><a class=\"article-inline-link article-citation\" href=\"#verapamil-augmentation-lithium-treatment-improves-outcome-mania-unresponsive-lithium\" data-reference-link=\"\" aria-label=\"Source: Mallinger, A. G., Thase, M. E., Haskett, R., Buttenfield, J., Luckenbaugh, D. A., Frank, E., Kupfer, D. J., &amp; Manji, H. K. (2008). Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to Lithium Alone: Preliminary Findings and a Discussion of Therapeutic Mechanisms. Bipolar Disorders, 10(8), 856–866. Retrieved from Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to…\">[4]</a></p><h2 id=\"how-does-verapamil-work\">How does verapamil work?</h2><p>Verapamil blocks calcium from entering certain parts of the brain, which results in the relaxation of the brain and heart muscle and a reduction of certain brain activity. <sup><a class=\"article-inline-link article-citation\" href=\"#verapamil\" data-reference-link=\"\" aria-label=\"Source: Fahie, S., &amp; Cassagnol, M. (2022). Verapamil. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from National Library of Medicine\">[1]</a></sup><sup><a class=\"article-inline-link article-citation\" href=\"#systematic-review-calcium-channel-antagonists-bipolar-disorder-some-considerations\" data-reference-link=\"\" aria-label=\"Source: Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. Molecular Psychiatry, 21(10), 1324–1332. Retrieved from A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…\">[2]</a></sup></p><p>Its established uses concern cardiovascular conditions; a mood-stabilizing benefit should not be assumed. [3]</p><h2 id=\"how-is-verapamil-usually-taken\">How is verapamil usually taken?</h2><p>Verapamil is available an oral tablet, both immediate-release and extended-release, and as an extended-release capsule.</p><p>Tablets must be swallowed whole without being crushed or broken.</p><p>Capsules should be swallowed whole without crushing. Alternatively, they can be opened, and the medication sprinkled over a soft food, such as applesauce, which can then be swallowed without chewing.</p><p>Immediate-release verapamil is generally taken 3-4 times per day, as the medication is released and absorbed into the body very quickly. On the other hand, extended-release medication is generally taken 1-2 times per day, as it is released more slowly into the body, having a longer-lasting effect.</p><p>Your doctor will likely initially prescribe you a low dose of verapamil, closely monitoring any changes in your physical or mental state. This dose can then be increased gradually to find the most effective dose for you.</p><p>Your dose may depend on the severity of your condition, your age, weight, and response to the medication.</p><p>Ensure you take your medication exactly as prescribed, using the correct type of verapamil, the correct dose, and the correct times, for the duration of the medical treatment.</p><p>If you forget one dose, take it as soon as you remember, or if it is near your next dose, skip the missed dose and take the next. Never take double your prescribed dose, as adverse effects can occur.</p><h2 id=\"how-long-does-verapamil-stay-in-your-system\">How long does verapamil stay in your system?</h2><p>When you start taking verapamil, you may notice some changes in your symptoms within the first week or two, although it may take several weeks for the medication to take full effect.</p><p>After verapamil is stopped, it may take 1-2 weeks for the medication to fully leave your system, depending on the dosage and length of your treatment. <sup><a class=\"article-inline-link article-citation\" href=\"#pharmacokinetics-conventional-slow-release-verapamil\" data-reference-link=\"\" aria-label=\"Source: Follath, F., Ha, H. R., Schütz, E., &amp; Bühler, F. (1986). Pharmacokinetics of Conventional and Slow-Release Verapamil. British Journal of Clinical Pharmacology, 21 Suppl 2(Suppl 2), 149S–153S. Retrieved from Pharmacokinetics of Conventional and Slow-Release Verapamil\">[5]</a></sup></p><p>Never suddenly stop taking verapamil, even if you feel better, as this can cause adverse effects on both your mental and physical health. However, if your doctor advises that it is safe to stop taking this medication, they will likely reduce your dose slowly to prevent adverse effects.</p><h2 id=\"verapamil-side-effects\">Verapamil side effects</h2><p>When you start a new medication, you may experience some common side effects. These should reduce within the first week or two, but if they continue or become problematic, consult your doctor, as you may need a change of dose or medication.</p><p>Common side effects of verapamil include:</p><ul class=\"wp-block-list\">\n<li>Heartburn</li>\n<li>Constipation</li>\n<li>Dizziness</li>\n<li>Headache</li>\n</ul><p>Serious side effects of verapamil are less common but may still occur. If you experience any of the following, contact your doctor immediately:</p><ul class=\"wp-block-list\">\n<li>Extreme tiredness</li>\n<li>Swelling of the hands or feet</li>\n<li>Breathing difficulties</li>\n<li>Fainting</li>\n<li>Blurry vision</li>\n<li>Unexplained bruising or bleeding</li>\n<li>Loss of appetite or weight</li>\n<li>Stomach pain</li>\n<li>Yellowing of the face or eyes</li>\n<li>Fever or sweating</li>\n</ul><h2 id=\"verapamil-precautions\">Verapamil precautions</h2><p>Discuss with your doctor all your past and present physical health conditions, as this may impact your ability to take verapamil safely.</p><p>Because of the potential side effects, you may not be able to take this medication if you have experienced certain heart, liver, kidney, digestive, muscular, or breathing-related conditions. However, if your doctor deems it necessary for you to take this medication, they will closely monitor any changes in your physical health, and you may be prescribed a lower dose.</p><p>It is important that your doctor is aware of any past or present mental health conditions you have experienced to enable safe monitoring of your condition while on this medication or to decide if it is safe for you.</p><p>Tell your doctor and pharmacist about all medications you are taking or plan to take (including vitamins and dietary supplements), as they may cause adverse reactions.</p><p>Inform your doctor if you are pregnant or planning to become pregnant. Verapamil may harm your fetus, so it is important that you are aware of the risks so that you can make an informed decision about your treatment. If it is deemed necessary to take this medication while pregnant, your doctor will closely monitor the physical health of your fetus, particularly heart functioning.<sup><a class=\"article-inline-link article-citation\" href=\"#verapamil\" data-reference-link=\"\" aria-label=\"Source: Fahie, S., &amp; Cassagnol, M. (2022). Verapamil. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from National Library of Medicine\">[1]</a></sup></p><p>If you are breastfeeding, it may be safe to take this medication. However, very small amounts of verapamil may pass to your baby through breast milk, so it is advised to use it cautiously and to carefully monitor your baby for any unusual changes in its physical or mental state.</p><section aria-label=\"Subject matter expert\" class=\"article-expert article-expert-inline\" data-expert-kind=\"related\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"/assets/optimized/90339bb61ace127cee8df5f2.webp\" width=\"64\" decoding=\"async\"><h2><a href=\"/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h2></div><p class=\"article-expert-focus\">Clinical pharmacy and medication</p><a class=\"profile-experience-link experience-button\" href=\"/people/leila-khurshid\">View experience</a></section><h2 id=\"verapamil-interactions\">Verapamil interactions</h2><p>Some medications or substances may interact with verapamil, impacting the effectiveness of the medication or increasing the risk of serious side effects. This includes some antibiotic and antifungal medications, beta blockers, diuretics, blood pressure medication, lithium, St. John’s wort, and some other psychiatric medications.</p><p>It is advised to avoid or limit alcohol use while taking verapamil, as the medication can increase the effects of alcohol <sup><a class=\"article-inline-link article-citation\" href=\"#verapamil-medlineplus-drug-information\" data-reference-link=\"\" aria-label=\"Source: Verapamil: MedlinePlus Drug Information. (Revised 2017). MedlinePlus. Retrieved from MedlinePlus\">[6]</a></sup>.</p><p>Large amounts of grapefruit or grapefruit juice should not be consumed with verapamil, as it can increase the effects of the medication, increasing the risk of side effects.</p><h2 id=\"verapamil-storage\">Verapamil storage</h2><p>Always keep all medications out of reach of children.</p><p>Store verapamil in its original packaging, in airtight containers, and at room temperature (never above 86 F).</p><p>If you need to dispose of medication that is expired or no longer needed, contact a medical professional to ensure it is disposed of appropriately. Never flush medications down the toilet or put them in the trash, as this can create unnecessary risks.</p><h2 id=\"what-to-do-if-you-overdose-on-verapamil\">What to do if you overdose on verapamil</h2><p>If you overdose on verapamil, call a medical professional or Poison Control at 1-800-222-1222, or in case of an emergency, call 911. Symptoms of a verapamil overdose include breathing difficulties, feeling dizzy, irregular heartbeat, seizure, coma, or even death.</p><h2 id=\"faqs\">FAQs</h2><h3 id=\"how-long-does-verapamil-take-to-work\">How long does verapamil take to work?</h3><p>Verapamil may take up to two weeks to be in full effect. You may notice changes in your symptoms within this time. If you have not noticed any improvements within 2-3 months, inform your doctor, as it may be that this medication is not the best treatment for you, and you may need to try alternatives.<sup><a class=\"article-inline-link article-citation\" href=\"#systematic-review-calcium-channel-antagonists-bipolar-disorder-some-considerations\" data-reference-link=\"\" aria-label=\"Source: Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. Molecular Psychiatry, 21(10), 1324–1332. Retrieved from A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…\">[2]</a></sup><sup><a class=\"article-inline-link article-citation\" href=\"#pharmacokinetics-conventional-slow-release-verapamil\" data-reference-link=\"\" aria-label=\"Source: Follath, F., Ha, H. R., Schütz, E., &amp; Bühler, F. (1986). Pharmacokinetics of Conventional and Slow-Release Verapamil. British Journal of Clinical Pharmacology, 21 Suppl 2(Suppl 2), 149S–153S. Retrieved from Pharmacokinetics of Conventional and Slow-Release Verapamil\">[5]</a></sup></p><h3 id=\"are-there-any-alternatives-to-verapamil\">Are there any alternatives to verapamil?</h3><p>Common medication options for bipolar disorder include mood stabilizers, such as lithium or valproate, and certain antipsychotics. Different medicines may be used for current episodes and longer-term management. Antidepressants are not used alone for bipolar depression because they can trigger mania or rapid cycling. <a class=\"article-inline-link article-citation\" href=\"#treatment-bipolar-disorder\" data-reference-link=\"\" aria-label=\"Source: National Institute of Mental Health (2025). Bipolar Disorder. National Institutes of Health. Accessed October 8, 2026.\">[7]</a></p><p>You can discuss alternative medications with your doctor, who can advise you on the benefits and side effects of each medication so that you can make an informed decision about your treatment.</p><p>People often respond to medications differently, so what works for one person may not work for another. Therefore, you may need to try more than one or a combination of medications to find what works well for you.</p><p>You may also wish to engage in talking therapy alongside your medication, as this is often the most effective treatment plan to help you manage your condition.<sup><a class=\"article-inline-link article-citation\" href=\"#bipolar-disorder\" data-reference-link=\"\" aria-label=\"Source: Bipolar Disorder. (n.d.). NAMI. Retrieved from NAMI\">[8]</a></sup></p></article><div class=\"article-endmatter\"><section class=\"article-sources\" data-reference-list=\"\" data-reference-style=\"author-date-numbered\" data-source-references=\"\" id=\"references\"><h2 id=\"references-2\">References</h2><ol>\n<li data-reference-number=\"1\" id=\"verapamil\" data-legacy-reference=\"reference-1\">Fahie, S., &amp; Cassagnol, M. (2022). <em>Verapamil</em>. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from <a href=\"https://www.ncbi.nlm.nih.gov/books/NBK538495/?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">National Library of Medicine</a></li>\n<li data-reference-number=\"2\" id=\"systematic-review-calcium-channel-antagonists-bipolar-disorder-some-considerations\" data-legacy-reference=\"reference-2\">Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. <em>Molecular Psychiatry</em>, <em>21</em>(10), 1324–1332. Retrieved from <a href=\"https://www.nature.com/articles/mp201686?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…</a></li>\n<li data-reference-number=\"3\" id=\"verapamil-treatment-women-bipolar-disorder\" data-legacy-reference=\"reference-3\">Cipriani, A., Saunders, P. T. K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., &amp; Harrison, P. J. (2016). <a href=\"https://research.manchester.ac.uk/en/publications/a-systematic-review-of-calcium-channel-antagonists-in-bipolar-dis/?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development</a>. <i>Molecular Psychiatry, 21(10), 1324–1332</i>. Accessed October 8, 2026.</li>\n<li data-reference-number=\"4\" id=\"verapamil-augmentation-lithium-treatment-improves-outcome-mania-unresponsive-lithium\" data-legacy-reference=\"reference-4\">Mallinger, A. G., Thase, M. E., Haskett, R., Buttenfield, J., Luckenbaugh, D. A., Frank, E., Kupfer, D. J., &amp; Manji, H. K. (2008). Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to Lithium Alone: Preliminary Findings and a Discussion of Therapeutic Mechanisms. <em>Bipolar Disorders</em>, <em>10</em>(8), 856–866. Retrieved from <a href=\"https://onlinelibrary.wiley.com/doi/10.1111/j.1399-5618.2008.00636.x?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to…</a></li>\n<li data-reference-number=\"5\" id=\"pharmacokinetics-conventional-slow-release-verapamil\" data-legacy-reference=\"reference-5\">Follath, F., Ha, H. R., Schütz, E., &amp; Bühler, F. (1986). Pharmacokinetics of Conventional and Slow-Release Verapamil. <em>British Journal of Clinical Pharmacology</em>, <em>21 Suppl 2</em>(Suppl 2), 149S–153S. Retrieved from <a href=\"https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1986.tb02864.x?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">Pharmacokinetics of Conventional and Slow-Release Verapamil</a></li>\n<li data-reference-number=\"6\" id=\"verapamil-medlineplus-drug-information\" data-legacy-reference=\"reference-6\"><em>Verapamil: MedlinePlus Drug Information.</em> (Revised 2017). MedlinePlus. Retrieved from <a href=\"https://medlineplus.gov/druginfo/meds/a684030.html?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">MedlinePlus</a></li>\n<li data-reference-number=\"7\" id=\"treatment-bipolar-disorder\" data-legacy-reference=\"reference-7\">National Institute of Mental Health (2025). <a href=\"https://www.nimh.nih.gov/health/publications/bipolar-disorder?utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">Bipolar Disorder</a>. <i>National Institutes of Health</i>. Accessed October 8, 2026.</li>\n<li data-reference-number=\"8\" id=\"bipolar-disorder\" data-legacy-reference=\"reference-8\"><em>Bipolar Disorder. </em>(n.d.). NAMI. Retrieved from <a href=\"https://www.nami.org/types-of-conditions/bipolar-disorder/?tab=treatment&amp;utm_medium=referral&amp;utm_campaign=libra&amp;utm_content=external_resource&amp;utm_id=site-library-verapamil-uses-dosage-side-effects&amp;utm_source=mentalhealth.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">NAMI</a></li>\n</ol></section><section class=\"article-medical article-panel\"><h2 id=\"medical-content\">Medical Content</h2><p><a href=\"/clinical-affairs\">The Clinical Affairs Team</a> at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the <a href=\"/publishing/editorial-policy\">Editorial Policy</a>.</p></section><section class=\"article-about article-panel\"><h2 id=\"about-mentalhealth-com\">About MentalHealth.com</h2><p>MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.</p><div class=\"article-contributors\"><section class=\"article-bio\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"/assets/optimized/47686b37ff1465ff6711c0b5.jpg\" width=\"64\" decoding=\"async\"><div><p class=\"article-bio-role\">Author</p><h3 id=\"naomi-carr\"><a href=\"/people/naomi-carr\">Naomi Carr</a></h3><p class=\"article-bio-credentials\">Writer</p><p>Naomi Carr is a writer with a background in English Literature from Oxford Brookes University.</p><dl><div><dt>Published</dt><dd><time datetime=\"2024-08-06T23:36:40Z\">August 6, 2024</time></dd></div><div><dt>Updated</dt><dd><time datetime=\"2025-08-13T12:17:13Z\">August 13, 2025</time></dd></div></dl></div></section><section class=\"article-bio\"><img alt=\"\" height=\"64\" loading=\"lazy\" src=\"/assets/optimized/90339bb61ace127cee8df5f2.webp\" width=\"64\" decoding=\"async\"><div><p class=\"article-bio-role\">Medical Reviewer</p><h3 id=\"leila-khurshid-pharm-d\"><a href=\"/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h3><p class=\"article-bio-credentials\">Pharm.D., BCPS</p><p>Leila Khursid is a medical reviewer with a Doctor of Pharmacy degree and completed a PGY1 Pharmacy Residency from St. Mark's Hospital.</p><dl></dl></div></section></div></section><section aria-label=\"Related community\" class=\"article-topic-community article-topic-community-end\"><img alt=\"\" class=\"topic-community-banner\" height=\"48\" loading=\"lazy\" src=\"/assets/optimized/9ae511a8c567ef6fdff00197.webp\" width=\"48\" decoding=\"async\"><p class=\"topic-community-label\">Related community</p><h2>Medications</h2><p>Explore questions and perspectives about psychiatric medications and the treatment experience.</p><a href=\"/community/medications\">Explore community</a></section></div></div><aside aria-label=\"Article navigation and related information\" class=\"article-sidebar\" data-bounded-rail=\"\" tabindex=\"0\"><details class=\"article-contents\" data-expanded=\"false\" data-scrolled-past=\"false\" data-section-preview=\"3\" open=\"\"><summary><strong>Table of contents</strong><span aria-hidden=\"true\"></span><small data-current-section=\"\">Choose a section</small></summary><nav aria-label=\"Article contents\"><ol id=\"article-section-list\"><li><a aria-label=\"Verapamil brand names\" href=\"#verapamil-brand-names\" title=\"Verapamil brand names\">Verapamil brand names</a></li><li><a aria-label=\"What is verapamil prescribed for?\" href=\"#what-is-verapamil-prescribed-for\" title=\"What is verapamil prescribed for?\">What is verapamil prescribed for?</a></li><li><a aria-label=\"How does verapamil work?\" href=\"#how-does-verapamil-work\" title=\"How does verapamil work?\">How does verapamil work?</a></li><li><a aria-label=\"How is verapamil usually taken?\" href=\"#how-is-verapamil-usually-taken\" title=\"How is verapamil usually taken?\">How is verapamil usually taken?</a></li><li><a aria-label=\"How long does verapamil stay in your system?\" href=\"#how-long-does-verapamil-stay-in-your-system\" title=\"How long does verapamil stay in your system?\">How long does verapamil stay in your system?</a></li><li><a aria-label=\"Verapamil side effects\" href=\"#verapamil-side-effects\" title=\"Verapamil side effects\">Verapamil side effects</a></li><li><a aria-label=\"Verapamil precautions\" href=\"#verapamil-precautions\" title=\"Verapamil precautions\">Verapamil precautions</a></li><li><a aria-label=\"Verapamil interactions\" href=\"#verapamil-interactions\" title=\"Verapamil interactions\">Verapamil interactions</a></li><li><a aria-label=\"Verapamil storage\" href=\"#verapamil-storage\" title=\"Verapamil storage\">Verapamil storage</a></li><li><a aria-label=\"What to do if you overdose on verapamil\" href=\"#what-to-do-if-you-overdose-on-verapamil\" title=\"What to do if you overdose on verapamil\">What to do if you overdose on verapamil</a></li><li><a aria-label=\"FAQs\" href=\"#faqs\" title=\"FAQs\">FAQs</a></li></ol><button aria-controls=\"article-section-list\" aria-expanded=\"false\" class=\"article-sections-toggle\" data-sections-toggle=\"\" type=\"button\">View more</button></nav></details></aside></div></div></div>","text":"Home Library Medications Verapamil Verapamil Written by Naomi Carr Medically reviewed by Leila Khurshid, Pharm.D. Published on August 6, 2024 · Updated on August 13, 2025 Verapamil is a calcium-channel blocker used for treating various heart conditions and sometimes for the treatment of bipolar disorder. Take this medication exactly as prescribed. Always consult your doctor or pharmacist before starting a new medication (prescribed or over the counter) while taking verapamil, as adverse effects can occur. Key takeaways Verapamil is a calcium-channel blocker used for heart conditions and sometimes prescribed off-label for bipolar disorder. Formulations and treatment plans vary, and medication interactions can change its effects or increase risks. Medical supervision is important because adverse cardiovascular effects and overdose can be serious. Verapamil brand names Calan Calan SR Covera HS Isoptin (discontinued) Verelan Verelan PM What is verapamil prescribed for? Verapamil is prescribed to treat various heart conditions, including angina, high blood pressure, and tachycardia. [1] Verapamil has been investigated for bipolar disorder, but it is not an established treatment for acute mania. [2][3] Verapamil is not FDA-approved for bipolar disorder. A systematic review found no evidence of benefit in six controlled trials for acute mania. Its psychiatric use remains off-label, with limited evidence; any proposed use needs an individualized discussion with the prescriber. [2] [3] [4] How does verapamil work? Verapamil blocks calcium from entering certain parts of the brain, which results in the relaxation of the brain and heart muscle and a reduction of certain brain activity. [1] [2] Its established uses concern cardiovascular conditions; a mood-stabilizing benefit should not be assumed. [3] How is verapamil usually taken? Verapamil is available an oral tablet, both immediate-release and extended-release, and as an extended-release capsule. Tablets must be swallowed whole without being crushed or broken. Capsules should be swallowed whole without crushing. Alternatively, they can be opened, and the medication sprinkled over a soft food, such as applesauce, which can then be swallowed without chewing. Immediate-release verapamil is generally taken 3-4 times per day, as the medication is released and absorbed into the body very quickly. On the other hand, extended-release medication is generally taken 1-2 times per day, as it is released more slowly into the body, having a longer-lasting effect. Your doctor will likely initially prescribe you a low dose of verapamil, closely monitoring any changes in your physical or mental state. This dose can then be increased gradually to find the most effective dose for you. Your dose may depend on the severity of your condition, your age, weight, and response to the medication. Ensure you take your medication exactly as prescribed, using the correct type of verapamil, the correct dose, and the correct times, for the duration of the medical treatment. If you forget one dose, take it as soon as you remember, or if it is near your next dose, skip the missed dose and take the next. Never take double your prescribed dose, as adverse effects can occur. How long does verapamil stay in your system? When you start taking verapamil, you may notice some changes in your symptoms within the first week or two, although it may take several weeks for the medication to take full effect. After verapamil is stopped, it may take 1-2 weeks for the medication to fully leave your system, depending on the dosage and length of your treatment. [5] Never suddenly stop taking verapamil, even if you feel better, as this can cause adverse effects on both your mental and physical health. However, if your doctor advises that it is safe to stop taking this medication, they will likely reduce your dose slowly to prevent adverse effects. Verapamil side effects When you start a new medication, you may experience some common side effects. These should reduce within the first week or two, but if they continue or become problematic, consult your doctor, as you may need a change of dose or medication. Common side effects of verapamil include: Heartburn Constipation Dizziness Headache Serious side effects of verapamil are less common but may still occur. If you experience any of the following, contact your doctor immediately: Extreme tiredness Swelling of the hands or feet Breathing difficulties Fainting Blurry vision Unexplained bruising or bleeding Loss of appetite or weight Stomach pain Yellowing of the face or eyes Fever or sweating Verapamil precautions Discuss with your doctor all your past and present physical health conditions, as this may impact your ability to take verapamil safely. Because of the potential side effects, you may not be able to take this medication if you have experienced certain heart, liver, kidney, digestive, muscular, or breathing-related conditions. However, if your doctor deems it necessary for you to take this medication, they will closely monitor any changes in your physical health, and you may be prescribed a lower dose. It is important that your doctor is aware of any past or present mental health conditions you have experienced to enable safe monitoring of your condition while on this medication or to decide if it is safe for you. Tell your doctor and pharmacist about all medications you are taking or plan to take (including vitamins and dietary supplements), as they may cause adverse reactions. Inform your doctor if you are pregnant or planning to become pregnant. Verapamil may harm your fetus, so it is important that you are aware of the risks so that you can make an informed decision about your treatment. If it is deemed necessary to take this medication while pregnant, your doctor will closely monitor the physical health of your fetus, particularly heart functioning. [1] If you are breastfeeding, it may be safe to take this medication. However, very small amounts of verapamil may pass to your baby through breast milk, so it is advised to use it cautiously and to carefully monitor your baby for any unusual changes in its physical or mental state. Subject matter expert Leila Khurshid, Pharm.D. Clinical pharmacy and medication View experience Verapamil interactions Some medications or substances may interact with verapamil, impacting the effectiveness of the medication or increasing the risk of serious side effects. This includes some antibiotic and antifungal medications, beta blockers, diuretics, blood pressure medication, lithium, St. John’s wort, and some other psychiatric medications. It is advised to avoid or limit alcohol use while taking verapamil, as the medication can increase the effects of alcohol [6] . Large amounts of grapefruit or grapefruit juice should not be consumed with verapamil, as it can increase the effects of the medication, increasing the risk of side effects. Verapamil storage Always keep all medications out of reach of children. Store verapamil in its original packaging, in airtight containers, and at room temperature (never above 86 F). If you need to dispose of medication that is expired or no longer needed, contact a medical professional to ensure it is disposed of appropriately. Never flush medications down the toilet or put them in the trash, as this can create unnecessary risks. What to do if you overdose on verapamil If you overdose on verapamil, call a medical professional or Poison Control at 1-800-222-1222, or in case of an emergency, call 911. Symptoms of a verapamil overdose include breathing difficulties, feeling dizzy, irregular heartbeat, seizure, coma, or even death. FAQs How long does verapamil take to work? Verapamil may take up to two weeks to be in full effect. You may notice changes in your symptoms within this time. If you have not noticed any improvements within 2-3 months, inform your doctor, as it may be that this medication is not the best treatment for you, and you may need to try alternatives. [2] [5] Are there any alternatives to verapamil? Common medication options for bipolar disorder include mood stabilizers, such as lithium or valproate, and certain antipsychotics. Different medicines may be used for current episodes and longer-term management. Antidepressants are not used alone for bipolar depression because they can trigger mania or rapid cycling. [7] You can discuss alternative medications with your doctor, who can advise you on the benefits and side effects of each medication so that you can make an informed decision about your treatment. People often respond to medications differently, so what works for one person may not work for another. Therefore, you may need to try more than one or a combination of medications to find what works well for you. You may also wish to engage in talking therapy alongside your medication, as this is often the most effective treatment plan to help you manage your condition. [8] References Fahie, S., & Cassagnol, M. (2022). Verapamil . In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from National Library of Medicine Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., & Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. Molecular Psychiatry , 21 (10), 1324–1332. Retrieved from A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some… Cipriani, A., Saunders, P. T. K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., & Harrison, P. J. (2016). A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development . Molecular Psychiatry, 21(10), 1324–1332 . Accessed October 8, 2026. Mallinger, A. G., Thase, M. E., Haskett, R., Buttenfield, J., Luckenbaugh, D. A., Frank, E., Kupfer, D. J., & Manji, H. K. (2008). Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to Lithium Alone: Preliminary Findings and a Discussion of Therapeutic Mechanisms. Bipolar Disorders , 10 (8), 856–866. Retrieved from Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to… Follath, F., Ha, H. R., Schütz, E., & Bühler, F. (1986). Pharmacokinetics of Conventional and Slow-Release Verapamil. British Journal of Clinical Pharmacology , 21 Suppl 2 (Suppl 2), 149S–153S. Retrieved from Pharmacokinetics of Conventional and Slow-Release Verapamil Verapamil: MedlinePlus Drug Information. (Revised 2017). MedlinePlus. Retrieved from MedlinePlus National Institute of Mental Health (2025). Bipolar Disorder . National Institutes of Health . Accessed October 8, 2026. Bipolar Disorder. (n.d.). NAMI. Retrieved from NAMI Medical Content The Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy . About MentalHealth.com MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life. Author Naomi Carr Writer Naomi Carr is a writer with a background in English Literature from Oxford Brookes University. Published August 6, 2024 Updated August 13, 2025 Medical Reviewer Leila Khurshid, Pharm.D. Pharm.D., BCPS Leila Khursid is a medical reviewer with a Doctor of Pharmacy degree and completed a PGY1 Pharmacy Residency from St. Mark's Hospital. Related communities Medications Explore questions and perspectives about psychiatric medications and the treatment experience. Explore community Table of contents Choose a section Verapamil brand names What is verapamil prescribed for? How does verapamil work? How is verapamil usually taken? How long does verapamil stay in your system? 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(2022). Verapamil. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Retrieved from National Library of Medicine","links":[{"url":"https://www.ncbi.nlm.nih.gov/books/NBK538495/?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"National Library of Medicine"}],"url":"https://www.ncbi.nlm.nih.gov/books/NBK538495/?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":2,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#systematic-review-calcium-channel-antagonists-bipolar-disorder-some-considerations","text":"Cipriani, A., Saunders, K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., & Harrison, P. J. (2016). A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some Considerations for their Future Development. Molecular Psychiatry, 21(10), 1324–1332. Retrieved from A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…","links":[{"url":"https://www.nature.com/articles/mp201686?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"A Systematic Review of Calcium Channel Antagonists in Bipolar Disorder and Some…"}],"url":"https://www.nature.com/articles/mp201686?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":3,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#verapamil-treatment-women-bipolar-disorder","text":"Cipriani, A., Saunders, P. T. K., Attenburrow, M. J., Stefaniak, J., Panchal, P., Stockton, S., Lane, T. A., Tunbridge, E. M., Geddes, J. R., & Harrison, P. J. (2016). A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development. Molecular Psychiatry, 21(10), 1324–1332. Accessed October 8, 2026.","links":[{"url":"https://research.manchester.ac.uk/en/publications/a-systematic-review-of-calcium-channel-antagonists-in-bipolar-dis/?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development"}],"url":"https://research.manchester.ac.uk/en/publications/a-systematic-review-of-calcium-channel-antagonists-in-bipolar-dis/?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":4,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#verapamil-augmentation-lithium-treatment-improves-outcome-mania-unresponsive-lithium","text":"Mallinger, A. G., Thase, M. E., Haskett, R., Buttenfield, J., Luckenbaugh, D. A., Frank, E., Kupfer, D. J., & Manji, H. K. (2008). Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to Lithium Alone: Preliminary Findings and a Discussion of Therapeutic Mechanisms. Bipolar Disorders, 10(8), 856–866. Retrieved from Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to…","links":[{"url":"https://onlinelibrary.wiley.com/doi/10.1111/j.1399-5618.2008.00636.x?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"Verapamil Augmentation of Lithium Treatment Improves Outcome in Mania Unresponsive to…"}],"url":"https://onlinelibrary.wiley.com/doi/10.1111/j.1399-5618.2008.00636.x?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":5,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#pharmacokinetics-conventional-slow-release-verapamil","text":"Follath, F., Ha, H. R., Schütz, E., & Bühler, F. (1986). Pharmacokinetics of Conventional and Slow-Release Verapamil. British Journal of Clinical Pharmacology, 21 Suppl 2(Suppl 2), 149S–153S. Retrieved from Pharmacokinetics of Conventional and Slow-Release Verapamil","links":[{"url":"https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1986.tb02864.x?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"Pharmacokinetics of Conventional and Slow-Release Verapamil"}],"url":"https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1986.tb02864.x?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":6,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#verapamil-medlineplus-drug-information","text":"Verapamil: MedlinePlus Drug Information. (Revised 2017). MedlinePlus. Retrieved from MedlinePlus","links":[{"url":"https://medlineplus.gov/druginfo/meds/a684030.html?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"MedlinePlus"}],"url":"https://medlineplus.gov/druginfo/meds/a684030.html?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":7,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#treatment-bipolar-disorder","text":"National Institute of Mental Health (2025). Bipolar Disorder. National Institutes of Health. Accessed October 8, 2026.","links":[{"url":"https://www.nimh.nih.gov/health/publications/bipolar-disorder?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"Bipolar Disorder"}],"url":"https://www.nimh.nih.gov/health/publications/bipolar-disorder?utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"},{"number":8,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects#bipolar-disorder","text":"Bipolar Disorder. (n.d.). NAMI. Retrieved from NAMI","links":[{"url":"https://www.nami.org/types-of-conditions/bipolar-disorder/?tab=treatment&utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com","label":"NAMI"}],"url":"https://www.nami.org/types-of-conditions/bipolar-disorder/?tab=treatment&utm_medium=referral&utm_campaign=libra&utm_content=external_resource&utm_id=site-library-verapamil-uses-dosage-side-effects&utm_source=mentalhealth.com"}],"relatedReading":[],"links":[{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/","label":"Home"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library","label":"Library"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/medications","label":"Medications"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/naomi-carr","label":"Naomi 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Learn more about how it is used, interactions, and more.","canonical":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects","robots":"index,follow","socialImage":{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/optimized/ec9b0cb47c0207d45e88634d.png","width":1200,"height":630,"alt":"MentalHealth.com — Library","type":"image/png","sitemapGroup":"library"}},"breadcrumbs":[{"name":"Home","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/"},{"name":"Library","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library"},{"name":"Medications","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/medications"},{"name":"Verapamil","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/verapamil-uses-dosage-side-effects"}],"subjectMatterExpert":{"name":"Leila Khurshid, Pharm.D.","url":"/people/leila-khurshid","profileId":"2317","topic":"medication","focus":"Clinical pharmacy and medication","selectionBasis":"Documented expertise in the existing published profile","reviewAttribution":false},"keyTakeaways":["Verapamil is a calcium-channel blocker used for heart conditions and sometimes prescribed off-label for bipolar disorder.","Formulations and treatment plans vary, and medication interactions can change its effects or increase risks.","Medical supervision is important because adverse cardiovascular effects and overdose can be serious."],"introduction":{"html":"Verapamil is a calcium-channel blocker used for treating various heart conditions and sometimes for the treatment of bipolar disorder. Take this medication exactly as prescribed. Always consult your doctor or pharmacist before starting a new medication (prescribed or over the counter) while taking verapamil, as adverse effects can occur.","text":"Verapamil is a calcium-channel blocker used for treating various heart conditions and sometimes for the treatment of bipolar disorder. Take this medication exactly as prescribed. Always consult your doctor or pharmacist before starting a new medication (prescribed or over the counter) while taking verapamil, as adverse effects can occur.","sourceField":"hero"},"navigation":[{"label":"Verapamil brand names","href":"#verapamil-brand-names","heading":"Verapamil brand names"},{"label":"What is verapamil prescribed for?","href":"#what-is-verapamil-prescribed-for","heading":"What is verapamil prescribed for?"},{"label":"How does verapamil work?","href":"#how-does-verapamil-work","heading":"How does verapamil work?"},{"label":"How is verapamil usually taken?","href":"#how-is-verapamil-usually-taken","heading":"How is verapamil usually taken?"},{"label":"How long does verapamil stay in your system?","href":"#how-long-does-verapamil-stay-in-your-system","heading":"How long does verapamil stay in your system?"},{"label":"Verapamil side effects","href":"#verapamil-side-effects","heading":"Verapamil side effects"},{"label":"Verapamil precautions","href":"#verapamil-precautions","heading":"Verapamil precautions"},{"label":"Verapamil interactions","href":"#verapamil-interactions","heading":"Verapamil interactions"},{"label":"Verapamil storage","href":"#verapamil-storage","heading":"Verapamil storage"},{"label":"What to do if you overdose on verapamil","href":"#what-to-do-if-you-overdose-on-verapamil","heading":"What to do if you overdose on verapamil"},{"label":"FAQs","href":"#faqs","heading":"FAQs"}],"relatedCommunity":{"community":"/community/medications","basis":"topic match"},"referencePresentation":"Numbered author–date bibliography with linked source documents; n.d. denotes unavailable publication date.","collections":[]}