{"formatVersion":"1.1","id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects","path":"/library/isocarboxazid-uses-dosage-side-effects","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects","title":"Isocarboxazid","family":"Library detail","description":"Isocarboxazid is an antidepressant medication sometimes used to treat depression and some other mental disorders, but users should be aware of side effects.","language":"en-US","access":{"audience":"custom-shared-preview","indexable":true},"provenance":{"sourceUrl":"https://www.mentalhealth.com/library/isocarboxazid-uses-dosage-side-effects","wordpressId":"631","contentCompleteness":"complete","dateScope":"original-source"},"authors":[{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen#person","name":"Jenni Jacobsen, Ph.D.","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen"}],"reviewer":{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair#person","name":"Morgan Blair","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair"},"dates":{"datePublished":"2023-10-06T09:32:24Z","dateModified":"2025-08-24T19:58:33Z","lastReviewed":"2023-10-06"},"content":{"html":"<nav class=\"breadcrumbs\" aria-label=\"Breadcrumb\"><ol><li><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/\">Home</a></li><li><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library\">Library</a></li><li><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/medications\">Medications</a></li><li><span aria-current=\"page\">Isocarboxazid</span></li></ol></nav><div class=\"article-page article-standard\" data-library-standard><div class=\"article-main-grid\"><header class=\"article-heading\"><h1>Isocarboxazid</h1><p class=\"article-inline-credits\"><span>Written by <a class=\"article-credit-person\" href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/97.jpg\" alt=\"\" width=\"22\" height=\"22\" loading=\"lazy\">Jenni Jacobsen, Ph.D.</a></span><span>Medically reviewed by <a class=\"article-credit-person\" href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/3070.jpg\" alt=\"\" width=\"22\" height=\"22\" loading=\"lazy\">Morgan Blair</a></span></p><div class=\"article-dates\"><span>Published on <time datetime=\"2023-10-06T09:32:24Z\">October 6, 2023</time></span><span aria-hidden=\"true\"> · </span><span>Updated on <time datetime=\"2025-08-24T19:58:33Z\">August 24, 2025</time></span></div></header><div class=\"article-jumpbar\"></div><div class=\"article-layout\"><div class=\"article-reading\"><article class=\"prose\" id=\"article-content\"><div class=\"article-intro\" data-source-field=\"hero\"><p>Isocarboxazid is an antidepressant drug used to treat people who do not experience adequate symptom relief with other types of antidepressant medication. While it can be effective in the treatment of depression, isocarboxazid is not the first choice for treating this mental health condition, because of safety concerns, side effects, and dietary restrictions that come along with it <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup> <sup><a href=\"#monoamine-oxidase-inhibitors-maoi\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\">[2]</a></sup>.</p></div><figure class=\"article-feature\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/library/editorial-17116.webp\" alt=\"A counselor listens and takes notes during a conversation.\" width=\"1200\" height=\"800\" loading=\"eager\" decoding=\"async\"></figure><section class=\"article-takeaways\" aria-labelledby=\"key-takeaways\"><h2 id=\"key-takeaways\">Key takeaways</h2><ul><li>Isocarboxazid is a monoamine oxidase inhibitor generally used when other antidepressants have not provided adequate relief.</li><li>Dietary restrictions and potentially serious drug interactions make it a less common first treatment choice.</li><li>Careful medical review and monitoring are important because adverse reactions and overdose can be dangerous.</li></ul></section><span id=\"isocarboxazid-brand-names-in-the-united-states-isocarboxazid-is-most-commonly-marketed-under-the-brand-name-marplan\" class=\"section-anchor-alias\" data-section-alias=\"isocarboxazid-brand-names\" aria-hidden=\"true\"></span><h2 id=\"isocarboxazid-brand-names\">Isocarboxazid brand names</h2><p>\nIn the United States, isocarboxazid is most commonly marketed under the brand name Marplan <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>.\n</p><span id=\"what-is-isocarboxazid-prescribed-for-isocarboxazid-is-an\" class=\"section-anchor-alias\" data-section-alias=\"what-is-isocarboxazid-prescribed-for\" aria-hidden=\"true\"></span><h2 id=\"what-is-isocarboxazid-prescribed-for\">What is isocarboxazid prescribed for?</h2><p>\nIsocarboxazid is an <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/antidepressants\" class=\"article-inline-link\">antidepressant drug</a>, but it can be prescribed for multiple psychiatric conditions. It is used to treat not only major depressive disorder, but also <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/dysthymic-disorder\" class=\"article-inline-link\">dysthymia (persistent depression)</a>, <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/panic-attacks-in-anxiety-disorders\" class=\"article-inline-link\">panic disorder</a>, and <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/specific-phobias\" class=\"article-inline-link\">phobias</a> <sup><a href=\"#isocarboxazid\" aria-label=\"Reference 3\" class=\"article-inline-link article-citation\">[3]</a></sup>. Given the safety concerns associated with this medication, it is not a first line of treatment for any mental health disorder. Rather, it is prescribed in patients who do not respond to other medications <sup><a href=\"#monoamine-oxidase-inhibitors-maoi\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\">[2]</a></sup>.\n</p><span id=\"how-does-isocarboxazid-work-isocarboxazid-belongs-to-a-class-of-drugs-called\" class=\"section-anchor-alias\" data-section-alias=\"how-does-isocarboxazid-work\" aria-hidden=\"true\"></span><h2 id=\"how-does-isocarboxazid-work\">How does isocarboxazid work?</h2><p>\nIsocarboxazid belongs to a class of drugs called <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/maois\" class=\"article-inline-link\">monoamine oxidase inhibitors (MAOI)</a>. As the name suggests, this drug class works by blocking activity of the monoamine oxidase enzyme, which is responsible for breaking down numerous neurotransmitters, including dopamine, tyramine, serotonin, and norepinephrine <sup><a href=\"#monoamine-oxidase-inhibitors-maoi\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\">[2]</a></sup>.\nBy blocking the activity of the monoamine oxidase enzyme, isocarboxazid stops the breakdown of these neurotransmitters, and increases their availability in the nervous system. This allows the neurotransmitters to act upon the cells that are affected by depression and related psychiatric disorders <sup><a href=\"#monoamine-oxidase-inhibitors-maoi\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\">[2]</a></sup>.\n</p><span id=\"how-is-isocarboxazid-usually-taken-isocarboxazid-comes-in-tablet-form-and-is-taken-by-mouth-usually-between-two-and-four-times-per-day-the-medication-is-available-as-a-10-mg-tablet-it-s-important-to-take-this-medication-exactly-as-prescribed-your-doctor-and-pharmacist-will-be-able-to-tell-you-how-often-to-take-isocarboxazid\" class=\"section-anchor-alias\" data-section-alias=\"how-is-isocarboxazid-usually-taken\" aria-hidden=\"true\"></span><h2 id=\"how-is-isocarboxazid-usually-taken\">How is isocarboxazid usually taken?</h2><p>\nIsocarboxazid comes in tablet form and is taken by mouth, usually between two and four times per day. The medication is available as a 10 mg tablet. It’s important to take this medication exactly as prescribed. Your doctor and pharmacist will be able to tell you how often to take isocarboxazid <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup> <sup><a href=\"#isocarboxazid\" aria-label=\"Reference 3\" class=\"article-inline-link article-citation\">[3]</a></sup>.\n</p><span id=\"how-long-does-isocarboxazid-stay-in-your-system-isocarboxazid-is-rapidly-metabolized-by-the-liver-the-medication-has-a-half-life-of-1-5-to-4-hours-which-is-the-amount-of-time-it-takes-half-of-the-original-dose-of-the-drug-to-leave-the-system-most-of-a-drug-is-eliminated-from-the-body-after-4-to-5-half-lives-meaning-that-it-takes-6-to-20-hours-for-isocarboxazid-to-leave-the-system\" class=\"section-anchor-alias\" data-section-alias=\"how-long-does-isocarboxazid-stay-in-your-system\" aria-hidden=\"true\"></span><h2 id=\"how-long-does-isocarboxazid-stay-in-your-system\">How long does isocarboxazid stay in your system?</h2><p>\nIsocarboxazid is rapidly metabolized by the liver. The medication has a half-life of 1.5 to 4 hours, which is the amount of time it takes half of the original dose of the drug to leave the system. Most of a drug is eliminated from the body after 4 to 5 half-lives, meaning that it takes 6 to 20 hours for isocarboxazid to leave the system <sup><a href=\"#isocarboxazid\" aria-label=\"Reference 3\" class=\"article-inline-link article-citation\">[3]</a></sup> <sup><a href=\"#half-life-national-library-medicine\" aria-label=\"Reference 4\" class=\"article-inline-link article-citation\">[4]</a></sup>.\n</p><span id=\"isocarboxazid-side-effects-isocarboxazid-like-any-medication-comes-with-side-effects-if-your-doctor-has-prescribed-this-medication-they-have-determined-that-the-benefits-of-the-medication-outweigh-the-potential-risk-of-adverse-effects-however-if-side-effects-are-severe-and-interfere-with-daily-life-it-s-important-to-discuss-them-with-your-doctor-common-side-effects-of-isocarboxazid-include\" class=\"section-anchor-alias\" data-section-alias=\"isocarboxazid-side-effects\" aria-hidden=\"true\"></span><h2 id=\"isocarboxazid-side-effects\">Isocarboxazid side effects</h2><p>\nIsocarboxazid, like any medication, comes with side effects. If your doctor has prescribed this medication, they have determined that the benefits of the medication outweigh the potential risk of adverse effects. However, if side effects are severe and interfere with daily life, it’s important to discuss them with your doctor.\nCommon side effects of isocarboxazid include <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>:\n</p><ul>\n    <li>Dryness in the mouth</li>\n    <li>Constipation</li>\n    <li>Diarrhea</li>\n    <li>Weakness</li>\n    <li>Severe fatigue</li>\n    <li>Forgetfulness</li>\n    <li>Reduced sexual performance</li>\n    <li>Difficulty or pain during urination</li>\n    <li>Urinating more frequently than usual</li>\n</ul><p>\nThe side effects above are often considered mild, and they may improve with time. More severe side effects associated with isocarboxazid include:\n</p><ul>\n    <li>Headache</li>\n    <li>Racing heart or chest pain</li>\n    <li>Fever or sweating</li>\n    <li>Chills</li>\n    <li>Cold, clammy skin</li>\n    <li>Dizziness</li>\n    <li>Feelings of tightness in the chest or throat</li>\n    <li>Neckstiffness or pain</li>\n    <li>Nausea and/or vomiting</li>\n    <li>Fainting</li>\n    <li>Blurred vision</li>\n    <li>Sensitivity to light</li>\n    <li>Increased pupil size</li>\n    <li>Yellowing in the skin or eyes</li>\n    <li>Uncontrollable shaking in any part of the body</li>\n    <li>Sudden jerking movements</li>\n    <li>Seizures</li>\n    <li>Numbness or tingling in the limbs</li>\n</ul><p>\nIf you experience severe side effects, contact your doctor immediately, or present to an emergency room for immediate medical care.\n</p><span id=\"isocarboxazid-precautions-in-addition-to-being-mindful-of-potential-side-effects-it-s-essential-to-be-aware-of-the-following-safety-precautions-that-apply-when-taking-isocarboxazid\" class=\"section-anchor-alias\" data-section-alias=\"isocarboxazid-precautions\" aria-hidden=\"true\"></span><h2 id=\"isocarboxazid-precautions\">Isocarboxazid precautions</h2><p>\nIn addition to being mindful of potential side effects, it’s essential to be aware of the following safety precautions that apply when taking isocarboxazid <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>:\n</p><ul>\n    <li>You must tell your doctor about all other medications and supplements you’re taking, as some of them may interact with isocarboxazid.</li>\n    <li>This medication can make you very drowsy, and you shouldn’t drive, operate heavy machinery, climb, or fly a plane until you confirm how significantly isocarboxazid affects you.</li>\n    <li>You’ll likely need to get out of bed slowly while taking isocarboxazid, because the medication can cause dizziness and fainting, especially when you get up quickly.</li>\n    <li>If you’re pregnant or plan to become pregnant, it’s important to discuss this with your doctor before taking isocarboxazid.</li>\n    <li>Before having any surgery, including dental surgery, it’s important to tell the surgeon that you’re taking isocarboxazid.</li>\n    <li>If you’re taking medication for nausea or diabetes, it’s essential that you tell your doctor before beginning isocarboxazid, as the dosages of your other medications may need to be changed.</li>\n    <li>Monoamine oxidase inhibitors like isocarboxazid can cause liver injury in rare cases. If you have a history of liver disease, it’s important to discuss this with your doctor before beginning this medication <sup><a href=\"#livertox-clinical-research-information-drug-induced-liver-injury\" aria-label=\"Reference 5\" class=\"article-inline-link article-citation\">[5]</a></sup>.</li>\n</ul><span id=\"isocarboxazid-interactions-there-are-various-substances-and-medications-that-can-cause-potentially-dangerous-interactions-when-taken-in-combination-with-isocarboxazid-which-is-why-it-s-essential-to-tell-your-doctor-about-all-substances-and-medications-you-re-using-the-following-substances-are-known-to-cause-potential-interactions-with-isocarboxazid-but-there-are-additional-medications-that-could-also-be-problematic\" class=\"section-anchor-alias\" data-section-alias=\"isocarboxazid-interactions\" aria-hidden=\"true\"></span><h2 id=\"isocarboxazid-interactions\">Isocarboxazid interactions</h2><p>\nThere are various substances and medications that can cause potentially dangerous interactions when taken in combination with isocarboxazid, which is why it’s essential to tell your doctor about all substances and medications you’re using. The following substances are known to cause potential interactions with isocarboxazid, but there are additional medications that could also be problematic <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup> <sup><a href=\"#monoamine-oxidase-inhibitors-maoi\" aria-label=\"Reference 2\" class=\"article-inline-link article-citation\">[2]</a></sup> <sup><a href=\"#fda\" aria-label=\"Reference 6\" class=\"article-inline-link article-citation\">[6]</a></sup>:\n</p><ul>\n    <li><strong>Other antidepressant drugs</strong>: Taking isocarboxazid in combination with other antidepressant drugs, such as selective serotoninreuptake inhibitors (SSRIs) like Prozac or Zoloft, can cause serotonin syndrome, which is potentially fatal. Symptoms include fever, sweating, confusion, seizures, fluctuations in heart rhythm and blood pressure, and organ problems. Given this risk, isocarboxazid should not be taken alongside other antidepressants.</li>\n    <li><strong>Tyramine-containing foods: </strong>Dietary restrictions required when taking isocarboxazid can be significant, because this medication can interact with tyramine-containing foods, causing an increase in blood pressure that can lead to hemorrhage. Tyramine levels increase as foods age, which means that patients taking isocarboxazid should avoid leftovers and choose fresh foods. Other tyramine-containing foods that can cause dangerous interactions include sausage, turkey, liver, salami, cheeses, fava beans, and overripe fruits, such as bananas, avocados, raisins, and figs.</li>\n    <li><strong>Alcohol: </strong>Alcohol can increase the drowsiness caused by isocarboxazid and should not be consumed while taking this medication.</li>\n    <li><strong>Opioids</strong>: Opioid drugs like Tramadol and Demerol can also increase ther isk of serotonin syndrome and should not be taken with isocarboxazid.</li>\n    <li><strong>Bupropion: </strong>Bupropion, the substance in brand name drugs including Wellbutrin and Zyban, should not be taken with isocarboxazid.</li>\n    <li><strong>Buspirone: </strong>When used with buspirone, a medication for the treatment of anxiety, isocarboxazid can cause dangerously elevated blood pressure.</li>\n    <li><strong>Stimulant Drugs: </strong>Stimulant medications, including Attention-deficit/hyperactivity disorder (ADHD) drugs such as Ritalin and Adderall, can cause hypertension and other severe adverse reactionsin combination with isocarboxazid.</li>\n    <li><strong>Drugs used in the treatment of Parkinson disease:</strong>Medications, including Levodopa, which are used to treat symptoms of Parkinson disease, can cause hypertension, headaches, and other serious side effects when used with isocarboxazid.</li>\n    <li><strong>Cough medication</strong>: The cough medication dextromethorphan should not be used with isocarboxazid, as the interaction of these two medications can lead to bizarre or psychotic behavior.</li>\n    <li><strong>Antihypertensive drugs: </strong>Isocarboxazid should not be used with antihypertensive drugs, which are used to treat high blood pressure, as thesedrug interactions can cause dangerously low blood pressure.</li>\n    <li><strong>CNS Depressants: </strong>Any medication or substance that depresses, or slows, the activity of the central nervous system (CNS) has the potential to cause dangerous interactions with isocarboxazid. Some of these substances have been mentioned elsewhere, but some CNS depressants that can be harmful include alcohol, narcotic drugs, and barbiturates.</li>\n</ul><p>\nThe list above is not exhaustive and does not include every specific medication that can interact with isocarboxazid, so you must consult with a doctor about the potential interaction between isocarboxazid and any medications you’re taking.\n</p><span id=\"isocarboxazid-storage-isocarboxazid-should-be-stored-at-room-temperature-it-should-not-be-kept-in-a-bathroom-since-it-should-be-away-from-excess-heat-and-moisture-keep-the-medication-in-its-original-container-out-of-reach-of-children-keeping-isocarboxazid-in-a-pill-container-or-in-other-locations-where-children-can-reach-it-could-result-in-unintentional-poisoning\" class=\"section-anchor-alias\" data-section-alias=\"isocarboxazid-storage\" aria-hidden=\"true\"></span><h2 id=\"isocarboxazid-storage\">Isocarboxazid storage</h2><p>\nIsocarboxazid should be stored at room temperature. It should not be kept in a bathroom, since it should be away from excess heat and moisture. Keep the medication in its original container, out of reach of children. Keeping isocarboxazid in a pill container or in other locations where children can reach it could result in unintentional poisoning <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>.\n</p><span id=\"what-to-do-if-you-overdose-on-isocarboxazid-isocarboxazid-can-result-in-overdose-symptoms-of-overdose-include-elevated-heart-rate-dizziness-fainting-blurred-vision-seizures-slowed-breathing-or-reflexes-fever-sweating-nausea-and-coma\" class=\"section-anchor-alias\" data-section-alias=\"what-to-do-if-you-overdose-on-isocarboxazid\" aria-hidden=\"true\"></span><h2 id=\"what-to-do-if-you-overdose-on-isocarboxazid\">What to do if you overdose on isocarboxazid</h2><p>\nIsocarboxazid can result in overdose. Symptoms of overdose include elevated heart rate, dizziness, fainting, blurred vision, seizures, slowed breathing or reflexes, fever, sweating, nausea, and coma <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>.\n</p><p>If you or someone you know shows signs of isocarboxazid overdose, contact poison control immediately. If a person has collapsed, is non-responsive, has a seizure, or has trouble breathing, call 911 or take them to the emergency room immediately <sup><a href=\"#retrieved-august-9-2023-medlineplus\" aria-label=\"Reference 1\" class=\"article-inline-link article-citation\">[1]</a></sup>.</p></article><div class=\"article-endmatter\"><section class=\"article-sources\" id=\"references\" data-source-references=\"\" data-reference-list=\"\" data-reference-style=\"author-date-numbered\"><h2 id=\"references-2\">References</h2><ol>\n    <li id=\"retrieved-august-9-2023-medlineplus\" data-reference-number=\"1\">National Library of Medicine. (2016). Retrieved August 9, 2023, from <u><a href=\"https://medlineplus.gov/druginfo/meds/a605036.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">MedlinePlus</a></u></li>\n    <li id=\"monoamine-oxidase-inhibitors-maoi\" data-reference-number=\"2\">Sub Labah, T., &amp; Saadabadi, A. (2022). Monoamine oxidase inhibitors (MAOI). National Library of Medicine. Retrieved August 9, 2023, from <a href=\"https://www.ncbi.nlm.nih.gov/books/NBK539848/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">National Library of Medicine</a></li>\n    <li id=\"isocarboxazid\" data-reference-number=\"3\">DrugBank Online. (2021). Isocarboxazid. Retrieved August 9, 2023, from <a href=\"https://go.drugbank.com/drugs/DB01247\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">DrugBank</a></li>\n    <li id=\"half-life-national-library-medicine\" data-reference-number=\"4\">Hallare, J., &amp; Gerriets, V. (2023). Half life.National Library of Medicine. Retrieved August 10, 2023 from <a href=\"https://www.ncbi.nlm.nih.gov/books/NBK554498/#:~:text=Understanding%20the%20concept%20of%20half,is%20removed%20from%20the%20body\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">National Library of Medicine</a>.</li>\n    <li id=\"livertox-clinical-research-information-drug-induced-liver-injury\" data-reference-number=\"5\">National Institute of Diabetes and Digestive and Kidney Diseases. (2012). LiverTox: Clinical and research information on drug-induced liver injury. National Library of Medicine. Retrieved August 10, 2023 from <a href=\"https://www.ncbi.nlm.nih.gov/books/NBK548518/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">National Library of Medicine</a></li>\n    <li id=\"fda\" data-reference-number=\"6\">Validus Pharmaceuticals. (2007). FDA. Retrieved August 10, 2023 from <a href=\"https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011961s039lbl.pdf\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">U.S. Food and Drug Administration</a></li>\n</ol></section><section class=\"article-medical article-panel\"><h2 id=\"medical-content\">Medical Content</h2><p><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/clinical-affairs\">The Clinical Affairs Team</a> at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the <a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/publishing/editorial-policy\">Editorial Policy</a>.</p></section><section class=\"article-about article-panel\"><h2 id=\"about-mentalhealth-com\">About MentalHealth.com</h2><p>MentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.</p><div class=\"article-contributors\"><section class=\"article-bio\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/97.jpg\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><div><p class=\"article-bio-role\">Author</p><h3 id=\"jenni-jacobsen-ph-d\"><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen\">Jenni Jacobsen, Ph.D.</a></h3><p class=\"article-bio-credentials\">Ph.D., LSW, MSW</p><p>Jenni Jacobsen, Ph.D. is a licensed social worker, behavioral health consultant and medical reviewer. She holds a Ph.D. in clinical psychology.</p><dl><div><dt>Published</dt><dd><time datetime=\"2023-10-06T09:32:24Z\">October 6, 2023</time></dd></div><div><dt>Updated</dt><dd><time datetime=\"2025-08-24T19:58:33Z\">August 24, 2025</time></dd></div></dl></div></section><section class=\"article-bio\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/3070.jpg\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><div><p class=\"article-bio-role\">Medical Reviewer</p><h3 id=\"morgan-blair\"><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair\">Morgan Blair</a></h3><p class=\"article-bio-credentials\">MA, LPCC</p><p>Morgan Blair is a licensed therapist, writer and medical reviewer, holding a master’s degree in clinical mental health counseling from Northwestern University.</p><dl><div><dt>Reviewed</dt><dd><time datetime=\"2023-10-06\">October 6, 2023</time></dd></div></dl></div></section></div></section><section class=\"article-expert article-expert-mobile\" aria-label=\"Subject matter expert\" data-expert-kind=\"related\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/3060.webp\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><h2><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h2></div><p class=\"article-expert-focus\">Clinical pharmacy and medication</p><a class=\"profile-experience-link experience-button\" href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid\">View experience</a></section><section class=\"article-topic-community article-topic-community-mobile\" aria-label=\"Related communities\"><img class=\"topic-community-banner\" src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/library/editorial-17234.webp\" alt=\"\" width=\"48\" height=\"48\" loading=\"lazy\"><p class=\"topic-community-label\">Related communities</p><h2>Medications</h2><p>Explore questions and perspectives about psychiatric medications and the treatment experience.</p><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/community/medications\">Explore community</a></section></div></div><aside class=\"article-sidebar\" tabindex=\"0\" data-bounded-rail=\"\" aria-label=\"Article navigation and related information\"><details class=\"article-contents\" open data-section-preview=\"3\" data-expanded=\"false\" data-scrolled-past=\"false\"><summary><strong>Table of contents</strong><span aria-hidden=\"true\"></span><small data-current-section=\"\">Choose a section</small></summary><nav aria-label=\"Article contents\"><ol id=\"article-section-list\"><li><a href=\"#isocarboxazid-brand-names\" title=\"Isocarboxazid brand names\" aria-label=\"Isocarboxazid brand names\">Isocarboxazid brand names</a></li><li><a href=\"#what-is-isocarboxazid-prescribed-for\" title=\"What is isocarboxazid prescribed for?\" aria-label=\"What is isocarboxazid prescribed for?\">What is isocarboxazid prescribed for?</a></li><li><a href=\"#how-does-isocarboxazid-work\" title=\"How does isocarboxazid work?\" aria-label=\"How does isocarboxazid work?\">How does isocarboxazid work?</a></li><li><a href=\"#how-is-isocarboxazid-usually-taken\" title=\"How is isocarboxazid usually taken?\" aria-label=\"How is isocarboxazid usually taken?\">How is isocarboxazid usually taken?</a></li><li><a href=\"#how-long-does-isocarboxazid-stay-in-your-system\" title=\"How long does isocarboxazid stay in your system?\" aria-label=\"How long does isocarboxazid stay in your system?\">How long does isocarboxazid stay in your system?</a></li><li><a href=\"#isocarboxazid-side-effects\" title=\"Isocarboxazid side effects\" aria-label=\"Isocarboxazid side effects\">Isocarboxazid side effects</a></li><li><a href=\"#isocarboxazid-precautions\" title=\"Isocarboxazid precautions\" aria-label=\"Isocarboxazid precautions\">Isocarboxazid precautions</a></li><li><a href=\"#isocarboxazid-interactions\" title=\"Isocarboxazid interactions\" aria-label=\"Isocarboxazid interactions\">Isocarboxazid interactions</a></li><li><a href=\"#isocarboxazid-storage\" title=\"Isocarboxazid storage\" aria-label=\"Isocarboxazid storage\">Isocarboxazid storage</a></li><li><a href=\"#what-to-do-if-you-overdose-on-isocarboxazid\" title=\"What to do if you overdose on isocarboxazid\" aria-label=\"What to do if you overdose on isocarboxazid\">What to do if you overdose on isocarboxazid</a></li></ol><button type=\"button\" class=\"article-sections-toggle\" data-sections-toggle aria-controls=\"article-section-list\" aria-expanded=\"false\">View more</button></nav></details><section class=\"article-expert\" aria-label=\"Subject matter expert\" data-expert-kind=\"related\"><p class=\"article-bio-role\">Subject matter expert</p><div class=\"article-expert-identity\"><img src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/3060.webp\" alt=\"\" width=\"64\" height=\"64\" loading=\"lazy\"><h2><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid\">Leila Khurshid, Pharm.D.</a></h2></div><p class=\"article-expert-focus\">Clinical pharmacy and medication</p><a class=\"profile-experience-link experience-button\" href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/leila-khurshid\">View experience</a></section><section class=\"article-topic-community\" aria-label=\"Related communities\"><img class=\"topic-community-banner\" src=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/library/editorial-17234.webp\" alt=\"\" width=\"48\" height=\"48\" loading=\"lazy\"><p class=\"topic-community-label\">Related communities</p><h2>Medications</h2><p>Explore questions and perspectives about psychiatric medications and the treatment experience.</p><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/community/medications\">Explore community</a></section></aside></div></div></div>","text":"HomeLibraryMedicationsIsocarboxazidIsocarboxazidWritten by Jenni Jacobsen, Ph.D.Medically reviewed by Morgan BlairPublished on October 6, 2023 · Updated on August 24, 2025Isocarboxazid is an antidepressant drug used to treat people who do not experience adequate symptom relief with other types of antidepressant medication. While it can be effective in the treatment of depression, isocarboxazid is not the first choice for treating this mental health condition, because of safety concerns, side effects, and dietary restrictions that come along with it [1] [2].Key takeawaysIsocarboxazid is a monoamine oxidase inhibitor generally used when other antidepressants have not provided adequate relief.Dietary restrictions and potentially serious drug interactions make it a less common first treatment choice.Careful medical review and monitoring are important because adverse reactions and overdose can be dangerous.Isocarboxazid brand names In the United States, isocarboxazid is most commonly marketed under the brand name Marplan [1]. What is isocarboxazid prescribed for? Isocarboxazid is an antidepressant drug, but it can be prescribed for multiple psychiatric conditions. It is used to treat not only major depressive disorder, but also dysthymia (persistent depression), panic disorder, and phobias [3]. Given the safety concerns associated with this medication, it is not a first line of treatment for any mental health disorder. Rather, it is prescribed in patients who do not respond to other medications [2]. How does isocarboxazid work? Isocarboxazid belongs to a class of drugs called monoamine oxidase inhibitors (MAOI). As the name suggests, this drug class works by blocking activity of the monoamine oxidase enzyme, which is responsible for breaking down numerous neurotransmitters, including dopamine, tyramine, serotonin, and norepinephrine [2]. By blocking the activity of the monoamine oxidase enzyme, isocarboxazid stops the breakdown of these neurotransmitters, and increases their availability in the nervous system. This allows the neurotransmitters to act upon the cells that are affected by depression and related psychiatric disorders [2]. How is isocarboxazid usually taken? Isocarboxazid comes in tablet form and is taken by mouth, usually between two and four times per day. The medication is available as a 10 mg tablet. It’s important to take this medication exactly as prescribed. Your doctor and pharmacist will be able to tell you how often to take isocarboxazid [1] [3]. How long does isocarboxazid stay in your system? Isocarboxazid is rapidly metabolized by the liver. The medication has a half-life of 1.5 to 4 hours, which is the amount of time it takes half of the original dose of the drug to leave the system. Most of a drug is eliminated from the body after 4 to 5 half-lives, meaning that it takes 6 to 20 hours for isocarboxazid to leave the system [3] [4]. Isocarboxazid side effects Isocarboxazid, like any medication, comes with side effects. If your doctor has prescribed this medication, they have determined that the benefits of the medication outweigh the potential risk of adverse effects. However, if side effects are severe and interfere with daily life, it’s important to discuss them with your doctor. Common side effects of isocarboxazid include [1]: Dryness in the mouth Constipation Diarrhea Weakness Severe fatigue Forgetfulness Reduced sexual performance Difficulty or pain during urination Urinating more frequently than usual The side effects above are often considered mild, and they may improve with time. More severe side effects associated with isocarboxazid include: Headache Racing heart or chest pain Fever or sweating Chills Cold, clammy skin Dizziness Feelings of tightness in the chest or throat Neckstiffness or pain Nausea and/or vomiting Fainting Blurred vision Sensitivity to light Increased pupil size Yellowing in the skin or eyes Uncontrollable shaking in any part of the body Sudden jerking movements Seizures Numbness or tingling in the limbs If you experience severe side effects, contact your doctor immediately, or present to an emergency room for immediate medical care. Isocarboxazid precautions In addition to being mindful of potential side effects, it’s essential to be aware of the following safety precautions that apply when taking isocarboxazid [1]: You must tell your doctor about all other medications and supplements you’re taking, as some of them may interact with isocarboxazid. This medication can make you very drowsy, and you shouldn’t drive, operate heavy machinery, climb, or fly a plane until you confirm how significantly isocarboxazid affects you. You’ll likely need to get out of bed slowly while taking isocarboxazid, because the medication can cause dizziness and fainting, especially when you get up quickly. If you’re pregnant or plan to become pregnant, it’s important to discuss this with your doctor before taking isocarboxazid. Before having any surgery, including dental surgery, it’s important to tell the surgeon that you’re taking isocarboxazid. If you’re taking medication for nausea or diabetes, it’s essential that you tell your doctor before beginning isocarboxazid, as the dosages of your other medications may need to be changed. Monoamine oxidase inhibitors like isocarboxazid can cause liver injury in rare cases. If you have a history of liver disease, it’s important to discuss this with your doctor before beginning this medication [5]. Isocarboxazid interactions There are various substances and medications that can cause potentially dangerous interactions when taken in combination with isocarboxazid, which is why it’s essential to tell your doctor about all substances and medications you’re using. The following substances are known to cause potential interactions with isocarboxazid, but there are additional medications that could also be problematic [1] [2] [6]: Other antidepressant drugs: Taking isocarboxazid in combination with other antidepressant drugs, such as selective serotoninreuptake inhibitors (SSRIs) like Prozac or Zoloft, can cause serotonin syndrome, which is potentially fatal. Symptoms include fever, sweating, confusion, seizures, fluctuations in heart rhythm and blood pressure, and organ problems. Given this risk, isocarboxazid should not be taken alongside other antidepressants. Tyramine-containing foods: Dietary restrictions required when taking isocarboxazid can be significant, because this medication can interact with tyramine-containing foods, causing an increase in blood pressure that can lead to hemorrhage. Tyramine levels increase as foods age, which means that patients taking isocarboxazid should avoid leftovers and choose fresh foods. Other tyramine-containing foods that can cause dangerous interactions include sausage, turkey, liver, salami, cheeses, fava beans, and overripe fruits, such as bananas, avocados, raisins, and figs. Alcohol: Alcohol can increase the drowsiness caused by isocarboxazid and should not be consumed while taking this medication. Opioids: Opioid drugs like Tramadol and Demerol can also increase ther isk of serotonin syndrome and should not be taken with isocarboxazid. Bupropion: Bupropion, the substance in brand name drugs including Wellbutrin and Zyban, should not be taken with isocarboxazid. Buspirone: When used with buspirone, a medication for the treatment of anxiety, isocarboxazid can cause dangerously elevated blood pressure. Stimulant Drugs: Stimulant medications, including Attention-deficit/hyperactivity disorder (ADHD) drugs such as Ritalin and Adderall, can cause hypertension and other severe adverse reactionsin combination with isocarboxazid. Drugs used in the treatment of Parkinson disease:Medications, including Levodopa, which are used to treat symptoms of Parkinson disease, can cause hypertension, headaches, and other serious side effects when used with isocarboxazid. Cough medication: The cough medication dextromethorphan should not be used with isocarboxazid, as the interaction of these two medications can lead to bizarre or psychotic behavior. Antihypertensive drugs: Isocarboxazid should not be used with antihypertensive drugs, which are used to treat high blood pressure, as thesedrug interactions can cause dangerously low blood pressure. CNS Depressants: Any medication or substance that depresses, or slows, the activity of the central nervous system (CNS) has the potential to cause dangerous interactions with isocarboxazid. Some of these substances have been mentioned elsewhere, but some CNS depressants that can be harmful include alcohol, narcotic drugs, and barbiturates. The list above is not exhaustive and does not include every specific medication that can interact with isocarboxazid, so you must consult with a doctor about the potential interaction between isocarboxazid and any medications you’re taking. Isocarboxazid storage Isocarboxazid should be stored at room temperature. It should not be kept in a bathroom, since it should be away from excess heat and moisture. Keep the medication in its original container, out of reach of children. Keeping isocarboxazid in a pill container or in other locations where children can reach it could result in unintentional poisoning [1]. What to do if you overdose on isocarboxazid Isocarboxazid can result in overdose. Symptoms of overdose include elevated heart rate, dizziness, fainting, blurred vision, seizures, slowed breathing or reflexes, fever, sweating, nausea, and coma [1]. If you or someone you know shows signs of isocarboxazid overdose, contact poison control immediately. If a person has collapsed, is non-responsive, has a seizure, or has trouble breathing, call 911 or take them to the emergency room immediately [1].References National Library of Medicine. (2016). Retrieved August 9, 2023, from MedlinePlus Sub Labah, T., & Saadabadi, A. (2022). Monoamine oxidase inhibitors (MAOI). National Library of Medicine. Retrieved August 9, 2023, from National Library of Medicine DrugBank Online. (2021). Isocarboxazid. Retrieved August 9, 2023, from DrugBank Hallare, J., & Gerriets, V. (2023). Half life.National Library of Medicine. Retrieved August 10, 2023 from National Library of Medicine. National Institute of Diabetes and Digestive and Kidney Diseases. (2012). LiverTox: Clinical and research information on drug-induced liver injury. National Library of Medicine. Retrieved August 10, 2023 from National Library of Medicine Validus Pharmaceuticals. (2007). FDA. Retrieved August 10, 2023 from U.S. Food and Drug Administration Medical ContentThe Clinical Affairs Team at MentalHealth.com is a dedicated group of medical professionals with diverse and extensive clinical experience. They actively contribute to the development of content, products, and services, and meticulously review all medical material before publication to ensure accuracy and alignment with current research and conversations in mental health. For more information, please visit the Editorial Policy.About MentalHealth.comMentalHealth.com helps people understand themselves, build healthier relationships, and access the right care. We bring together mental health education, diagnostics, and care management to support well-being throughout every phase of life.AuthorJenni Jacobsen, Ph.D.Ph.D., LSW, MSWJenni Jacobsen, Ph.D. is a licensed social worker, behavioral health consultant and medical reviewer. She holds a Ph.D. in clinical psychology.PublishedOctober 6, 2023UpdatedAugust 24, 2025Medical ReviewerMorgan BlairMA, LPCCMorgan Blair is a licensed therapist, writer and medical reviewer, holding a master’s degree in clinical mental health counseling from Northwestern University.ReviewedOctober 6, 2023Subject matter expertLeila Khurshid, Pharm.D.Clinical pharmacy and medicationView experienceRelated communitiesMedicationsExplore questions and perspectives about psychiatric medications and the treatment experience.Explore communityTable of contentsChoose a sectionIsocarboxazid brand namesWhat is isocarboxazid prescribed for?How does isocarboxazid work?How is isocarboxazid usually taken?How long does isocarboxazid stay in your system?Isocarboxazid side effectsIsocarboxazid precautionsIsocarboxazid interactionsIsocarboxazid storageWhat to do if you overdose on isocarboxazidView moreSubject matter expertLeila Khurshid, Pharm.D.Clinical pharmacy and medicationView experienceRelated communitiesMedicationsExplore questions and perspectives about psychiatric medications and the treatment experience.Explore community","wordCount":1753},"schema":{"@context":"https://schema.org","@graph":[{"@type":"Organization","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/#organization","name":"MentalHealth.com","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/"},{"@type":"WebSite","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/#website","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/","name":"MentalHealth.com","inLanguage":"en-US","publisher":{"@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/#organization"}},{"@type":"BreadcrumbList","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://mentalhealth-v2.workspace-454808.chatgpt.site/"},{"@type":"ListItem","position":2,"name":"Library","item":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library"},{"@type":"ListItem","position":3,"name":"Medications","item":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/medications"},{"@type":"ListItem","position":4,"name":"Isocarboxazid","item":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects"}]},{"@type":"ImageObject","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#primaryimage","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/library/editorial-17116.webp","contentUrl":"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/library/editorial-17116.webp","width":1200,"height":800,"encodingFormat":"image/webp","caption":"A counselor listens and takes notes during a conversation."},{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen#person","name":"Jenni Jacobsen, Ph.D.","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen","jobTitle":"Ph.D., LSW, MSW","image":"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/97.jpg"},{"@type":"Person","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair#person","name":"Morgan Blair","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair","jobTitle":"MA, LPCC","image":"https://mentalhealth-v2.workspace-454808.chatgpt.site/assets/wordpress/3070.jpg","sameAs":["https://www.linkedin.com/in/morgan-blair-5627aa88/"]},{"@type":"Article","@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#article","url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects","headline":"Isocarboxazid","description":"Isocarboxazid is an antidepressant medication sometimes used to treat depression and some other mental disorders, but users should be aware of side effects.","wordCount":1407,"mainEntityOfPage":{"@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#webpage"},"publisher":{"@id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/#organization"},"articleSection":"Library","citation":[{"@type":"CreativeWork","name":"National Library of Medicine. 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(2016). Retrieved August 9, 2023, from MedlinePlus","links":[{"url":"https://medlineplus.gov/druginfo/meds/a605036.html","label":"MedlinePlus"}],"url":"https://medlineplus.gov/druginfo/meds/a605036.html"},{"number":2,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#monoamine-oxidase-inhibitors-maoi","text":"Sub Labah, T., & Saadabadi, A. (2022). Monoamine oxidase inhibitors (MAOI). National Library of Medicine. Retrieved August 9, 2023, from National Library of Medicine","links":[{"url":"https://www.ncbi.nlm.nih.gov/books/NBK539848/","label":"National Library of Medicine"}],"url":"https://www.ncbi.nlm.nih.gov/books/NBK539848/"},{"number":3,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#isocarboxazid","text":"DrugBank Online. (2021). Isocarboxazid. Retrieved August 9, 2023, from DrugBank","links":[{"url":"https://go.drugbank.com/drugs/DB01247","label":"DrugBank"}],"url":"https://go.drugbank.com/drugs/DB01247"},{"number":4,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#half-life-national-library-medicine","text":"Hallare, J., & Gerriets, V. (2023). Half life.National Library of Medicine. Retrieved August 10, 2023 from National Library of Medicine.","links":[{"url":"https://www.ncbi.nlm.nih.gov/books/NBK554498/#:~:text=Understanding%20the%20concept%20of%20half,is%20removed%20from%20the%20body","label":"National Library of Medicine"}],"url":"https://www.ncbi.nlm.nih.gov/books/NBK554498/#:~:text=Understanding%20the%20concept%20of%20half,is%20removed%20from%20the%20body"},{"number":5,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#livertox-clinical-research-information-drug-induced-liver-injury","text":"National Institute of Diabetes and Digestive and Kidney Diseases. (2012). LiverTox: Clinical and research information on drug-induced liver injury. National Library of Medicine. Retrieved August 10, 2023 from National Library of Medicine","links":[{"url":"https://www.ncbi.nlm.nih.gov/books/NBK548518/","label":"National Library of Medicine"}],"url":"https://www.ncbi.nlm.nih.gov/books/NBK548518/"},{"number":6,"id":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#fda","text":"Validus Pharmaceuticals. (2007). FDA. Retrieved August 10, 2023 from U.S. Food and Drug Administration","links":[{"url":"https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011961s039lbl.pdf","label":"U.S. Food and Drug Administration"}],"url":"https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011961s039lbl.pdf"}],"relatedReading":[],"links":[{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/","label":"Home"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library","label":"Library"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/medications","label":"Medications"},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/jenni-jacobsen","label":"Jenni Jacobsen, Ph.D."},{"url":"https://mentalhealth-v2.workspace-454808.chatgpt.site/people/morgan-blair","label":"Morgan 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While it can be effective in the treatment of depression, isocarboxazid is not the first choice for treating this mental health condition, because of safety concerns, side effects, and dietary restrictions that come along with it <sup><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#resource-1\">[1]</a></sup> <sup><a href=\"https://mentalhealth-v2.workspace-454808.chatgpt.site/library/isocarboxazid-uses-dosage-side-effects#resource-2\">[2]</a></sup>.","text":"Isocarboxazid is an antidepressant drug used to treat people who do not experience adequate symptom relief with other types of antidepressant medication. 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